The current goals seem quite skewed to the oral cavity and oral health. It is difficult to clearly see where the 'craniofacial biology' component comes in.
There is little related to craniofacial research or diseases. Most of the goals relate to oral and dental health. It may be that this area should be attached to NIAMS and dropped from NIDCR, but then it should be done officially so that non-oral/dental researchers and clinicians find appropriate support.
There is no project related to the microbiome. Given the potential impact that mouth microbiome could have not only on oral/dental health but also on general health this is a missed opportunity.
There appears to be few opportunities for basic science research other than under the “Oral Health + Overall Health” block where ‘the understanding of the underlying biological cause of disease’ is clearly mentioned. Although this can be a topic of intense basic science research, the Institute should provide some kind of disease priorities based on incidence/epidemiology and cost to society.
Evaluation of the main oral health problems of approximately 6000 employees and 6000 dependents of a private hospital in Sao Paulo, Brazil.
Currently, between aspirin and morphine there are no better options to treat chronic pain! One of the viable approach is to identify and validate kinase inhibitors as potential new class of analgesics. There are many kinases known to be involved in modulating pain and their systematic study will be valuable towards this goal
From my own personal experience, Myofunctional... more »