Oral Health + Overall Health

Trained Immunity in the Oral Mucosa

Contrary to long-held perception, escalating evidence shows that innate immune cells can be “trained to remember”. Designated "trained immunity" or "innate immune memory", this process involves sustained (epigenetic) changes in transcriptional programs and enables innate immune cells to display enhanced responsiveness to secondary stimulation. This concept and its ramifications have important therapeutic applications in the context of oral immunity and homeostasis.

Comment No. 34