Tooth can be used as bioscaffold by decellularizing and demineralizing the permanent human tooth by controlled way of chemical use. The Extracellular matrix of the pulp and dentin acts as niche for the mesenchymal stem cell to grow and differentiate into odontoblasts and can recalcify the tooth again.Using autologous stem cell to reseed these scaffolds and then implanting them in the socket after immidiate extration can vascularize them. This can be paradigm shift for tooth regeneration.
Comment No. 51