Compromised oral and dental health in non communicable diseases(NCDs) such as diabetes, liver cirrhosis, advance kidney failure etc is documented in literature but HIV along with NCDs status is again great area which needs to be explored. Due to major organ failures, least importance is given to oral health problems nowdays leading to its increased severity, with cases terminating into oral malignancies also.
I would consider this work of assessing the relationship between HIV status along with NCDs or without NCDs and oral and dental health, to be of great importance to modulate the future therapeutic targets. Oral pathologies related to HIV are categorized as bacterial,viral, fungal and malignancies, but the exact mechanism for their prevalence and advancement in HIV and NCDs still remains unclear. Whether they are the result of tobacco habits, poor oral hygiene, presence of HIV, HIV with superimposed NCDs or use treatment with ART, necessitate further investigations. This needs tremendous work by evaluating the nature of oral disease,categorizing them, its prevalence along with NCDs and HIV, severity, effect of ART, their co relations and further treatment planning.
Immune suppression can be one of the areas to look upon and planning new modalities in such individuals.