Cellular & microbial interactions with the extracellular matrix in oral cavity calcified & non-calcified tissues are major determinants of structural & functional oral health. Proposed: multi-disciplinary approaches to increase understanding of multi-faceted roles of extracellular matrix (ECM) in craniofacial dev., inflammation & tissue repair, innate & adaptive immunity, microbial-host tissue interactions, and in dev. of ECM-based smart biomaterials for guided reg. of oral tissues & teeth.
Comment No. 172