Immune System Balance and Flexibility in Maintaining Good Oral Health

AADR: Efficacy of modern therapeutics against oral diseases.

As data has been gathered documenting roles for various host responses in the deleterious consequences of the persistent inflammation in periodontitis, as well as the unique feature of the resolution response biomolecules, modern tools for host response modulation (i.e., array of monoclonal antibody drugs for chronic inflammatory diseases) have generally not been evaluated related to periodontitis. If we are to increase the breadth and depth of the treatment toolbox for periodontitis in the 21st Century, studies of these therapeutics and their impacts on the gingival immune repertoire and immune system flexibility need to be implemented.

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Comment No. 357